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Inhibition of Dimethylarginine Dimethylaminohydrolase (DDAH) Enzymes as an Emerging Therapeutic Strategy to Target Angiogenesis and Vasculogenic Mimicry in Cancer

The small free radical gas nitric oxide (NO) plays a key role in various physiological and pathological processes through enhancement of endothelial cell survival and proliferation. In particular, NO has emerged as a molecule of interest in carcinogenesis and tumor progression due to its crucial rol...

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Detalles Bibliográficos
Autores principales: Hulin, Julie-Ann, Gubareva, Ekaterina A., Jarzebska, Natalia, Rodionov, Roman N., Mangoni, Arduino A., Tommasi, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962312/
https://www.ncbi.nlm.nih.gov/pubmed/31993367
http://dx.doi.org/10.3389/fonc.2019.01455