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Combination of Olanzapine and Samidorphan Has No Clinically Significant Effect on the Pharmacokinetics of Lithium or Valproate
BACKGROUND AND OBJECTIVE: Olanzapine is an atypical antipsychotic indicated for the treatment of schizophrenia and, either as monotherapy or as an adjunct to lithium or valproate, for bipolar I disorder. Multiple daily doses of olanzapine do not affect the pharmacokinetics of lithium or valproate; t...
Autores principales: | Sun, Lei, Yagoda, Sergey, Yao, Baiyun, Graham, Christine, von Moltke, Lisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962313/ https://www.ncbi.nlm.nih.gov/pubmed/31584140 http://dx.doi.org/10.1007/s40261-019-00860-y |
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