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Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9-mediated HDR in Atlantic salmon

Precise gene editing such as CRISPR/Cas9-mediated homology directed repair (HDR) can increase our understanding of gene function and improve traits of importance for aquaculture. This fine-tuned technology has not been developed for farmed fish including Atlantic salmon. We performed knock-in (KI) o...

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Detalles Bibliográficos
Autores principales:	Straume, Anne Hege, Kjærner-Semb, Erik, Ove Skaftnesmo, Kai, Güralp, Hilal, Kleppe, Lene, Wargelius, Anna, Edvardsen, Rolf Brudvik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962318/ https://www.ncbi.nlm.nih.gov/pubmed/31941961 http://dx.doi.org/10.1038/s41598-019-57295-w

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