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A Comorbidity Model of Myocardial Ischemia/Reperfusion Injury and Hypercholesterolemia in Rat Cardiac Myocyte Cultures

INTRODUCTION: The use of comorbidity models is crucial in cardioprotective drug development. Hypercholesterolemia causes endothelial and myocardial dysfunction, as well as aggravates ischemia/reperfusion (I/R)-induced myocardial injury. Endogenous cardioprotective mechanisms against I/R are impaired...

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Detalles Bibliográficos
Autores principales:	Makkos, András, Szántai, Ágnes, Pálóczi, János, Pipis, Judit, Kiss, Bernadett, Poggi, Paola, Ferdinandy, Péter, Chatgilialoglu, Alexandros, Görbe, Anikó
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962358/ https://www.ncbi.nlm.nih.gov/pubmed/31992989 http://dx.doi.org/10.3389/fphys.2019.01564

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