PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress

Cells subjected to stress situations mobilize specific membranes and proteins to initiate autophagy. Phosphatidylinositol-3-phosphate (PI3P), a crucial lipid in membrane dynamics, is known to be essential in this context. In addition to nutriments deprivation, autophagy is also triggered by fluid-fl...

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Detalles Bibliográficos
Autores principales: Boukhalfa, Asma, Nascimbeni, Anna Chiara, Ramel, Damien, Dupont, Nicolas, Hirsch, Emilio, Gayral, Stephanie, Laffargue, Muriel, Codogno, Patrice, Morel, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962367/
https://www.ncbi.nlm.nih.gov/pubmed/31941925
http://dx.doi.org/10.1038/s41467-019-14086-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962367/
https://www.ncbi.nlm.nih.gov/pubmed/31941925
http://dx.doi.org/10.1038/s41467-019-14086-1

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