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Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer
PURPOSE: Pancreatic cancer (PC) is one of the most lethal cancers worldwide, but there are currently no effective treatments. The DNA damage response (DDR) is under investigation for the development of novel anti-cancer drugs. Since DNA repair pathway alterations have been found frequently in PC, th...
Autores principales: | Jin, Mei Hua, Nam, Ah-Rong, Park, Ji Eun, Bang, Ju-Hee, Bang, Yung-Jue, Oh, Do-Youn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Cancer Association
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962488/ https://www.ncbi.nlm.nih.gov/pubmed/31291716 http://dx.doi.org/10.4143/crt.2019.183 |
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