Dual-specificity phosphatase (DUSP) genetic variants predict pulmonary hypertension in patients with bronchopulmonary dysplasia

BACKGROUND: Pulmonary hypertension (PH) in patients with bronchopulmonary (BPD) results from vasoconstriction and/or vascular remodeling, which can be regulated by mitogen-activated protein kinases (MAPK). MAPKs are deactivated by dual specificity phosphatases (DUSPs). We hypothesized that single nu...

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Detalles Bibliográficos
Autores principales: Chen, Lauren L, Zmuda, Erik J, Talavera, Maria M, Frick, Jessica, Brock, Guy, Liu, Yusen, Klebanoff, Mark A, Trittmann, Jennifer K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962530/
https://www.ncbi.nlm.nih.gov/pubmed/31330530
http://dx.doi.org/10.1038/s41390-019-0502-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962530/
https://www.ncbi.nlm.nih.gov/pubmed/31330530
http://dx.doi.org/10.1038/s41390-019-0502-9

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