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IMAGE-BASED β-ADRENERGIC SWEAT RATE ASSAY CAPTURES MINIMAL CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) FUNCTION
BACKGROUND: There is a need to prognosticate the severity of cystic fibrosis (CF) detected by newborn screening (NBS) by early assessment of CF Transmembrane Conductance Regulator protein function (CFTR). We introduce novel instrumentation and protocol for evaluating CFTR activity as reflected by β-...
Autores principales: | Salinas, Danieli Barino, Peng, Yu-Hao, Horwich, Brian, Wee, Choo Phei, Frisbee, Eric, Maarek, Jean-Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962560/ https://www.ncbi.nlm.nih.gov/pubmed/31344706 http://dx.doi.org/10.1038/s41390-019-0503-8 |
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