Intralingual and Intrapleural AAV Gene Therapy Prolongs Survival in a SOD1 ALS Mouse Model

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that results in death from respiratory failure. No cure exists for this devastating disease, but therapy that directly targets the respiratory system has the potential to prolong survival and improve quality of life in some cas...

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Detalles Bibliográficos
Autores principales: Keeler, Allison M., Zieger, Marina, Semple, Carson, Pucci, Logan, Veinbachs, Alessandra, Brown, Robert H., Mueller, Christian, ElMallah, Mai K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962641/
https://www.ncbi.nlm.nih.gov/pubmed/31970202
http://dx.doi.org/10.1016/j.omtm.2019.12.007

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