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Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin

Epigenetic mechanisms controlling adult mammalian stem cell (SC) dynamics might be critical for tissue regeneration but are poorly understood. Mouse skin and hair follicle SCs (HFSCs) display reduced histone H3 K4me3, K9me3, and K27me3 methylation levels (hypomethylation) preceding hair growth. Chem...

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Detalles Bibliográficos
Autores principales: Kang, Sangjo, Long, Kylie, Wang, Sherry, Sada, Aiko, Tumbar, Tudorita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962642/
https://www.ncbi.nlm.nih.gov/pubmed/31866458
http://dx.doi.org/10.1016/j.stemcr.2019.11.007