Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR

Genomic integrity of human pluripotent stem cells (hPSCs) is essential for research and clinical applications. However, genetic abnormalities can accumulate during hPSC generation and routine culture and following gene editing. Their occurrence should be regularly monitored, but the current assays t...

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Detalles Bibliográficos
Autores principales: Assou, Said, Girault, Nicolas, Plinet, Mathilde, Bouckenheimer, Julien, Sansac, Caroline, Combe, Marion, Mianné, Joffrey, Bourguignon, Chloé, Fieldes, Mathieu, Ahmed, Engi, Commes, Thérèse, Boureux, Anthony, Lemaître, Jean-Marc, De Vos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962701/
https://www.ncbi.nlm.nih.gov/pubmed/31902703
http://dx.doi.org/10.1016/j.stemcr.2019.12.004

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