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A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages

Ontologically distinct populations of macrophages differentially contribute to organ fibrosis through unknown mechanisms. We applied lineage tracing, single-cell RNA sequencing and single-molecule fluorescence in situ hybridisation to a spatially restricted model of asbestos-induced pulmonary fibros...

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Detalles Bibliográficos
Autores principales:	Joshi, Nikita, Watanabe, Satoshi, Verma, Rohan, Jablonski, Renea P., Chen, Ching-I, Cheresh, Paul, Markov, Nikolay S., Reyfman, Paul A., McQuattie-Pimentel, Alexandra C., Sichizya, Lango, Lu, Ziyan, Piseaux-Aillon, Raul, Kirchenbuechler, David, Flozak, Annette S., Gottardi, Cara J., Cuda, Carla M., Perlman, Harris, Jain, Manu, Kamp, David W., Budinger, G.R. Scott, Misharin, Alexander V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962769/ https://www.ncbi.nlm.nih.gov/pubmed/31601718 http://dx.doi.org/10.1183/13993003.00646-2019

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