A Single and Un-Adjuvanted Dose of a Chimpanzee Adenovirus-Vectored Vaccine against Chikungunya Virus Fully Protects Mice from Lethal Disease

The mosquito-borne chikungunya virus (CHIKV) has become a major global health problem. Upon infection, chikungunya fever (CHIKF) can result in long-term joint pain and arthritis, and despite intense research, no licensed vaccine for CHIKV is available. We have developed two recombinant chimpanzee ad...

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Detalles Bibliográficos
Autores principales: Campos, Rafael Kroon, Preciado-Llanes, Lorena, Azar, Sasha R., Lopez-Camacho, Cesar, Reyes-Sandoval, Arturo, Rossi, Shannan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963200/
https://www.ncbi.nlm.nih.gov/pubmed/31718104
http://dx.doi.org/10.3390/pathogens8040231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963200/
https://www.ncbi.nlm.nih.gov/pubmed/31718104
http://dx.doi.org/10.3390/pathogens8040231

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