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Animal Models of Type III Secretion System-Mediated Pathogenesis

The type III secretion system (T3SS) is a conserved virulence factor used by many Gram-negative pathogenic bacteria and has become an important target for anti-virulence drugs. Most T3SS inhibitors to date have been discovered using in vitro screening assays. Pharmacokinetics and other important cha...

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Detalles Bibliográficos
Autores principales: Hotinger, Julia A., May, Aaron E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963218/
https://www.ncbi.nlm.nih.gov/pubmed/31766664
http://dx.doi.org/10.3390/pathogens8040257