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Opening the OPK Assay Gatekeeper: Harnessing Multi-Modal Protection by Pneumococcal Vaccines

Pneumococcal vaccine development is driven by the achievement of high activity in a single gatekeeper assay: the bacterial opsonophagocytic killing (OPK) assay. New evidence challenges the dogma that anti-capsular antibodies have only a single function that predicts success. The emerging concept of...

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Detalles Bibliográficos
Autores principales:	Riegler, Ashleigh N., Mann, Beth, Orihuela, Carlos J., Tuomanen, Elaine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963391/ https://www.ncbi.nlm.nih.gov/pubmed/31652741 http://dx.doi.org/10.3390/pathogens8040203

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