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Exclusive Production of Gentamicin C1a from Micromonospora purpurea by Metabolic Engineering

Gentamicin C1a is an important precursor to the synthesis of etimicin, a potent antibiotic. Wild type Micromonospora purpurea Gb1008 produces gentamicin C1a, besides four other gentamicin C components: C1, C2, C2a, and C2b. While the previously reported engineered strain M. purpurea GK1101 can produ...

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Detalles Bibliográficos
Autores principales:	Wei, Zeng, Shi, Xianai, Lian, Rong, Wang, Weibin, Hong, Wenrong, Guo, Shaobin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963548/ https://www.ncbi.nlm.nih.gov/pubmed/31847403 http://dx.doi.org/10.3390/antibiotics8040267

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