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Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction

Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch–Schneider ri...

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Autores principales: Grottoli, Carlo Francesco, Cingolani, Alberto, Zambon, Fabio, Ferracini, Riccardo, Villa, Tomaso, Perale, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963854/
https://www.ncbi.nlm.nih.gov/pubmed/31766685
http://dx.doi.org/10.3390/jfb10040053
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author Grottoli, Carlo Francesco
Cingolani, Alberto
Zambon, Fabio
Ferracini, Riccardo
Villa, Tomaso
Perale, Giuseppe
author_facet Grottoli, Carlo Francesco
Cingolani, Alberto
Zambon, Fabio
Ferracini, Riccardo
Villa, Tomaso
Perale, Giuseppe
author_sort Grottoli, Carlo Francesco
collection PubMed
description Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch–Schneider ring). Moreover, valid alternatives and less invasive techniques still need to be supported by novel material development. In this work, we evaluated the performance of SmartBone(®), a xenohybrid bone graft composed of a bovine bone matrix reinforced with biodegradable polymers and collagen, as an effective support in acetabular prosthesis reconstruction. Specifically, the material’s mechanical properties were experimentally determined (E = ~1.25 GPa, E(f) = ~0.34 GPa, and Et = ~0.49 GPa) and used for simulation of the hip joint system with a SmartBone(®) insert. Moreover, a comparison with a similar case treated with a Burch–Schneider ring was also conducted. It was found that it is possible to perform THA revision surgeries without the insertion of an invasive metal support and it can be nicely combined with SmartBone(®)’s osteointegration characteristics. The material can withstand the loads independently (σ(max) = ~12 MPa) or be supported by a thinner titanium plate in contact with the bone in the worst cases. This way, improved bone regeneration can be achieved.
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spelling pubmed-69638542020-01-27 Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction Grottoli, Carlo Francesco Cingolani, Alberto Zambon, Fabio Ferracini, Riccardo Villa, Tomaso Perale, Giuseppe J Funct Biomater Article Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch–Schneider ring). Moreover, valid alternatives and less invasive techniques still need to be supported by novel material development. In this work, we evaluated the performance of SmartBone(®), a xenohybrid bone graft composed of a bovine bone matrix reinforced with biodegradable polymers and collagen, as an effective support in acetabular prosthesis reconstruction. Specifically, the material’s mechanical properties were experimentally determined (E = ~1.25 GPa, E(f) = ~0.34 GPa, and Et = ~0.49 GPa) and used for simulation of the hip joint system with a SmartBone(®) insert. Moreover, a comparison with a similar case treated with a Burch–Schneider ring was also conducted. It was found that it is possible to perform THA revision surgeries without the insertion of an invasive metal support and it can be nicely combined with SmartBone(®)’s osteointegration characteristics. The material can withstand the loads independently (σ(max) = ~12 MPa) or be supported by a thinner titanium plate in contact with the bone in the worst cases. This way, improved bone regeneration can be achieved. MDPI 2019-11-22 /pmc/articles/PMC6963854/ /pubmed/31766685 http://dx.doi.org/10.3390/jfb10040053 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Grottoli, Carlo Francesco
Cingolani, Alberto
Zambon, Fabio
Ferracini, Riccardo
Villa, Tomaso
Perale, Giuseppe
Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
title Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
title_full Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
title_fullStr Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
title_full_unstemmed Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
title_short Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
title_sort simulated performance of a xenohybrid bone graft (smartbone(®)) in the treatment of acetabular prosthetic reconstruction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963854/
https://www.ncbi.nlm.nih.gov/pubmed/31766685
http://dx.doi.org/10.3390/jfb10040053
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