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Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction
Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch–Schneider ri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963854/ https://www.ncbi.nlm.nih.gov/pubmed/31766685 http://dx.doi.org/10.3390/jfb10040053 |
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author | Grottoli, Carlo Francesco Cingolani, Alberto Zambon, Fabio Ferracini, Riccardo Villa, Tomaso Perale, Giuseppe |
author_facet | Grottoli, Carlo Francesco Cingolani, Alberto Zambon, Fabio Ferracini, Riccardo Villa, Tomaso Perale, Giuseppe |
author_sort | Grottoli, Carlo Francesco |
collection | PubMed |
description | Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch–Schneider ring). Moreover, valid alternatives and less invasive techniques still need to be supported by novel material development. In this work, we evaluated the performance of SmartBone(®), a xenohybrid bone graft composed of a bovine bone matrix reinforced with biodegradable polymers and collagen, as an effective support in acetabular prosthesis reconstruction. Specifically, the material’s mechanical properties were experimentally determined (E = ~1.25 GPa, E(f) = ~0.34 GPa, and Et = ~0.49 GPa) and used for simulation of the hip joint system with a SmartBone(®) insert. Moreover, a comparison with a similar case treated with a Burch–Schneider ring was also conducted. It was found that it is possible to perform THA revision surgeries without the insertion of an invasive metal support and it can be nicely combined with SmartBone(®)’s osteointegration characteristics. The material can withstand the loads independently (σ(max) = ~12 MPa) or be supported by a thinner titanium plate in contact with the bone in the worst cases. This way, improved bone regeneration can be achieved. |
format | Online Article Text |
id | pubmed-6963854 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69638542020-01-27 Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction Grottoli, Carlo Francesco Cingolani, Alberto Zambon, Fabio Ferracini, Riccardo Villa, Tomaso Perale, Giuseppe J Funct Biomater Article Total hip arthroplasty (THA) is a surgical procedure for the replacement of hip joints with artificial prostheses. Several approaches are currently employed in the treatment of this kind of defect. Overall, the most common method involves using a quite invasive metallic support (a Burch–Schneider ring). Moreover, valid alternatives and less invasive techniques still need to be supported by novel material development. In this work, we evaluated the performance of SmartBone(®), a xenohybrid bone graft composed of a bovine bone matrix reinforced with biodegradable polymers and collagen, as an effective support in acetabular prosthesis reconstruction. Specifically, the material’s mechanical properties were experimentally determined (E = ~1.25 GPa, E(f) = ~0.34 GPa, and Et = ~0.49 GPa) and used for simulation of the hip joint system with a SmartBone(®) insert. Moreover, a comparison with a similar case treated with a Burch–Schneider ring was also conducted. It was found that it is possible to perform THA revision surgeries without the insertion of an invasive metal support and it can be nicely combined with SmartBone(®)’s osteointegration characteristics. The material can withstand the loads independently (σ(max) = ~12 MPa) or be supported by a thinner titanium plate in contact with the bone in the worst cases. This way, improved bone regeneration can be achieved. MDPI 2019-11-22 /pmc/articles/PMC6963854/ /pubmed/31766685 http://dx.doi.org/10.3390/jfb10040053 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Grottoli, Carlo Francesco Cingolani, Alberto Zambon, Fabio Ferracini, Riccardo Villa, Tomaso Perale, Giuseppe Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction |
title | Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction |
title_full | Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction |
title_fullStr | Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction |
title_full_unstemmed | Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction |
title_short | Simulated Performance of a Xenohybrid Bone Graft (SmartBone(®)) in the Treatment of Acetabular Prosthetic Reconstruction |
title_sort | simulated performance of a xenohybrid bone graft (smartbone(®)) in the treatment of acetabular prosthetic reconstruction |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963854/ https://www.ncbi.nlm.nih.gov/pubmed/31766685 http://dx.doi.org/10.3390/jfb10040053 |
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