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Nucleobase Derivatives as Building Blocks to Form Ru(II)-Based Complexes with High Cytotoxicity

[Image: see text] Two new Ru(II)-based complexes containing 2-thiouracil derivatives, known as 2-thiouracil (2TU) and 6-methyl-2-thiouracil (6m2TU), were synthesized using cis,trans-[RuCl(2)(PPh(3))(2)(bipy)] as a precursor. The obtained compounds with a general formula trans-[Ru(2TU)(PPh(3))(2)(bip...

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Detalles Bibliográficos
Autores principales: Carvalho, Diogo E. L., Oliveira, Katia M., Bomfim, Larissa M., Soares, Milena B. P., Bezerra, Daniel P., Batista, Alzir A., Correa, Rodrigo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963899/
https://www.ncbi.nlm.nih.gov/pubmed/31956759
http://dx.doi.org/10.1021/acsomega.9b01921