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Nucleobase Derivatives as Building Blocks to Form Ru(II)-Based Complexes with High Cytotoxicity
[Image: see text] Two new Ru(II)-based complexes containing 2-thiouracil derivatives, known as 2-thiouracil (2TU) and 6-methyl-2-thiouracil (6m2TU), were synthesized using cis,trans-[RuCl(2)(PPh(3))(2)(bipy)] as a precursor. The obtained compounds with a general formula trans-[Ru(2TU)(PPh(3))(2)(bip...
Autores principales: | Carvalho, Diogo E. L., Oliveira, Katia M., Bomfim, Larissa M., Soares, Milena B. P., Bezerra, Daniel P., Batista, Alzir A., Correa, Rodrigo S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963899/ https://www.ncbi.nlm.nih.gov/pubmed/31956759 http://dx.doi.org/10.1021/acsomega.9b01921 |
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