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Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics

Purpose: Knowledge of the hemodynamics in the vascular system is important to understand and treat vascular pathology. The present study aimed to evaluate the hemodynamics in the human carotid artery bifurcation measured by four-dimensional (4D) flow magnetic resonance imaging (MRI) as compared to c...

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Autores principales: Ngo, Minh Tri, Kim, Chul In, Jung, Jinmu, Chung, Gyung Ho, Lee, Dong Hwan, Kwak, Hyo Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963916/
https://www.ncbi.nlm.nih.gov/pubmed/31847224
http://dx.doi.org/10.3390/diagnostics9040223
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author Ngo, Minh Tri
Kim, Chul In
Jung, Jinmu
Chung, Gyung Ho
Lee, Dong Hwan
Kwak, Hyo Sung
author_facet Ngo, Minh Tri
Kim, Chul In
Jung, Jinmu
Chung, Gyung Ho
Lee, Dong Hwan
Kwak, Hyo Sung
author_sort Ngo, Minh Tri
collection PubMed
description Purpose: Knowledge of the hemodynamics in the vascular system is important to understand and treat vascular pathology. The present study aimed to evaluate the hemodynamics in the human carotid artery bifurcation measured by four-dimensional (4D) flow magnetic resonance imaging (MRI) as compared to computational fluid dynamics (CFD). Methods: This protocol used MRI data of 12 healthy volunteers for the 3D vascular models and 4D flow MRI measurements for the boundary conditions in CFD simulation. We compared the velocities measured at the carotid bifurcation and the 3D velocity streamlines of the carotid arteries obtained by these two methods. Results: There was a good agreement for both maximum and minimum velocity values between the 2 methods for velocity magnitude at the bifurcation plane. However, on the 3D blood flow visualization, secondary flows, and recirculation regions are of poorer quality when visualized through the 4D flow MRI. Conclusion: 4D flow MRI and CFD show reasonable agreement in demonstrated velocity magnitudes at the carotid artery bifurcation. However, the visualization of blood flow at the recirculation regions and the assessment of secondary flow characteristics should be enhanced for the use of 4D flow MRI in clinical situations.
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spelling pubmed-69639162020-01-27 Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics Ngo, Minh Tri Kim, Chul In Jung, Jinmu Chung, Gyung Ho Lee, Dong Hwan Kwak, Hyo Sung Diagnostics (Basel) Article Purpose: Knowledge of the hemodynamics in the vascular system is important to understand and treat vascular pathology. The present study aimed to evaluate the hemodynamics in the human carotid artery bifurcation measured by four-dimensional (4D) flow magnetic resonance imaging (MRI) as compared to computational fluid dynamics (CFD). Methods: This protocol used MRI data of 12 healthy volunteers for the 3D vascular models and 4D flow MRI measurements for the boundary conditions in CFD simulation. We compared the velocities measured at the carotid bifurcation and the 3D velocity streamlines of the carotid arteries obtained by these two methods. Results: There was a good agreement for both maximum and minimum velocity values between the 2 methods for velocity magnitude at the bifurcation plane. However, on the 3D blood flow visualization, secondary flows, and recirculation regions are of poorer quality when visualized through the 4D flow MRI. Conclusion: 4D flow MRI and CFD show reasonable agreement in demonstrated velocity magnitudes at the carotid artery bifurcation. However, the visualization of blood flow at the recirculation regions and the assessment of secondary flow characteristics should be enhanced for the use of 4D flow MRI in clinical situations. MDPI 2019-12-13 /pmc/articles/PMC6963916/ /pubmed/31847224 http://dx.doi.org/10.3390/diagnostics9040223 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ngo, Minh Tri
Kim, Chul In
Jung, Jinmu
Chung, Gyung Ho
Lee, Dong Hwan
Kwak, Hyo Sung
Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics
title Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics
title_full Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics
title_fullStr Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics
title_full_unstemmed Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics
title_short Four-Dimensional Flow Magnetic Resonance Imaging for Assessment of Velocity Magnitudes and Flow Patterns in The Human Carotid Artery Bifurcation: Comparison with Computational Fluid Dynamics
title_sort four-dimensional flow magnetic resonance imaging for assessment of velocity magnitudes and flow patterns in the human carotid artery bifurcation: comparison with computational fluid dynamics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963916/
https://www.ncbi.nlm.nih.gov/pubmed/31847224
http://dx.doi.org/10.3390/diagnostics9040223
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