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Parenterally Administered P24-VP8* Nanoparticle Vaccine Conferred Strong Protection against Rotavirus Diarrhea and Virus Shedding in Gnotobiotic Pigs

Current live rotavirus vaccines are costly with increased risk of intussusception due to vaccine replication in the gut of vaccinated children. New vaccines with improved safety and cost-effectiveness are needed. In this study, we assessed the immunogenicity and protective efficacy of a novel P24-VP...

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Detalles Bibliográficos
Autores principales: Ramesh, Ashwin, Mao, Jiangdi, Lei, Shaohua, Twitchell, Erica, Shiraz, Ashton, Jiang, Xi, Tan, Ming, Yuan, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963946/
https://www.ncbi.nlm.nih.gov/pubmed/31698824
http://dx.doi.org/10.3390/vaccines7040177