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Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status

Measles has been reemerging in South Korea since December 2018 resulting in 185 cases by September 2019. We calculated contact-adjusted immunity levels against measles in South Korea using national seroprevalence data in 2014, vaccination uptake rates, and an age-specific contact matrix. We further...

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Autores principales: Chun, June Young, Park, Wan Beom, Kim, Nam Joong, Choi, Eun Hwa, Funk, Sebastian, Oh, Myoung-don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964151/
https://www.ncbi.nlm.nih.gov/pubmed/31679860
http://dx.doi.org/10.1016/j.vaccine.2019.10.040
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author Chun, June Young
Park, Wan Beom
Kim, Nam Joong
Choi, Eun Hwa
Funk, Sebastian
Oh, Myoung-don
author_facet Chun, June Young
Park, Wan Beom
Kim, Nam Joong
Choi, Eun Hwa
Funk, Sebastian
Oh, Myoung-don
author_sort Chun, June Young
collection PubMed
description Measles has been reemerging in South Korea since December 2018 resulting in 185 cases by September 2019. We calculated contact-adjusted immunity levels against measles in South Korea using national seroprevalence data in 2014, vaccination uptake rates, and an age-specific contact matrix. We further explored options to achieve a contact-adjusted immunity level of 93% for herd immunity. The assessed contact-adjusted immunity level has increased from 86% in 2014 to 92% in 2018. Herd immunity could be achieved with immunizing 50% of susceptibles among birth cohorts 1999–2003 in 2018. Contact-adjusted immunity levels against measles have increased recently in South Korea, although they might not yet be high enough to guarantee herd immunity.
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spelling pubmed-69641512020-01-22 Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status Chun, June Young Park, Wan Beom Kim, Nam Joong Choi, Eun Hwa Funk, Sebastian Oh, Myoung-don Vaccine Article Measles has been reemerging in South Korea since December 2018 resulting in 185 cases by September 2019. We calculated contact-adjusted immunity levels against measles in South Korea using national seroprevalence data in 2014, vaccination uptake rates, and an age-specific contact matrix. We further explored options to achieve a contact-adjusted immunity level of 93% for herd immunity. The assessed contact-adjusted immunity level has increased from 86% in 2014 to 92% in 2018. Herd immunity could be achieved with immunizing 50% of susceptibles among birth cohorts 1999–2003 in 2018. Contact-adjusted immunity levels against measles have increased recently in South Korea, although they might not yet be high enough to guarantee herd immunity. Elsevier Science 2020-01-10 /pmc/articles/PMC6964151/ /pubmed/31679860 http://dx.doi.org/10.1016/j.vaccine.2019.10.040 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chun, June Young
Park, Wan Beom
Kim, Nam Joong
Choi, Eun Hwa
Funk, Sebastian
Oh, Myoung-don
Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status
title Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status
title_full Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status
title_fullStr Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status
title_full_unstemmed Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status
title_short Estimating contact-adjusted immunity levels against measles in South Korea and prospects for maintaining elimination status
title_sort estimating contact-adjusted immunity levels against measles in south korea and prospects for maintaining elimination status
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964151/
https://www.ncbi.nlm.nih.gov/pubmed/31679860
http://dx.doi.org/10.1016/j.vaccine.2019.10.040
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