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Insights into the Binding Recognition and Susceptibility of Tofacitinib toward Janus Kinases

[Image: see text] Janus kinases (JAKs) are enzymes involved in signaling pathways that affect hematopoiesis and immune cell functions. JAK1, JAK2, and JAK3 play different roles in numerous diseases of the immune system and have also been considered as potential targets for cancer therapy. In the pre...

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Detalles Bibliográficos
Autores principales:	Sanachai, Kamonpan, Mahalapbutr, Panupong, Choowongkomon, Kiattawee, Poo-arporn, Rungtiva P., Wolschann, Peter, Rungrotmongkol, Thanyada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964278/ https://www.ncbi.nlm.nih.gov/pubmed/31956784 http://dx.doi.org/10.1021/acsomega.9b02800

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