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Phospholipase D2 in prostate cancer: protein expression changes with Gleason score

BACKGROUND: Phospholipases D1 and D2 (PLD1/2) are implicated in tumorigenesis through their generation of the signalling lipid phosphatidic acid and its downstream effects. Inhibition of PLD1 blocks prostate cell growth and colony formation. Here a role for PLD2 in prostate cancer (PCa), the major c...

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Detalles Bibliográficos
Autores principales:	Noble, Amanda R., Hogg, Karen, Suman, Rakesh, Berney, Daniel M., Bourgoin, Sylvain, Maitland, Norman J., Rumsby, Martin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964697/ https://www.ncbi.nlm.nih.gov/pubmed/31673104 http://dx.doi.org/10.1038/s41416-019-0610-7

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