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Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention

BACKGROUND: 3-Hydroxybutyrate dehydrogenase type 2 (BDH2) is known to catalyse a rate-limiting step in the biogenesis of the mammalian siderophore and regulate intracellular iron metabolism. Here we aim to explore the expression and possible function of BDH2 in nasopharyngeal carcinoma (NPC). METHOD...

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Detalles Bibliográficos
Autores principales:	Li, Bo, Liao, Zhipeng, Mo, Yingxi, Zhao, Weilin, Zhou, Xiaohui, Xiao, Xiling, Cui, Wanmeng, Feng, Guofei, Zhong, Suhua, Liang, Yushan, Du, Chunping, Huang, Guangwu, Li, Ping, Xiao, Xue, Zhou, Xiaoying, Wang, Rensheng, Zhang, Zhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964698/ https://www.ncbi.nlm.nih.gov/pubmed/31819181 http://dx.doi.org/10.1038/s41416-019-0638-8

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