Pyridinecarboxylic Acid Derivative Stimulates Pro-Angiogenic Mediators by PI3K/AKT/mTOR and Inhibits Reactive Nitrogen and Oxygen Species and NF-κB Activation Through a PPARγ-Dependent Pathway in T. cruzi-Infected Macrophages

Chagas disease is caused by Trypanosoma cruzi infection and represents an important public health concern in Latin America. Macrophages are one of the main infiltrating leukocytes in response to infection. Parasite persistence could trigger a sustained activation of these cells, contributing to the...

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Detalles Bibliográficos
Autores principales: Penas, Federico Nicolás, Carta, Davide, Cevey, Ágata Carolina, Rada, María Jimena, Pieralisi, Azul Victoria, Ferlin, María Grazia, Sales, María Elena, Mirkin, Gerardo A., Goren, Nora Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964702/
https://www.ncbi.nlm.nih.gov/pubmed/31993046
http://dx.doi.org/10.3389/fimmu.2019.02955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964702/
https://www.ncbi.nlm.nih.gov/pubmed/31993046
http://dx.doi.org/10.3389/fimmu.2019.02955

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