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Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis

PURPOSE: Detector‐dependent interinstitutional variations of the beam data may lead to uncertainties of the delivered dose to patients. Here we evaluated the inter‐unit variability of the flattened and flattening filter‐free (FFF) beam data of multiple TrueBeam (Varian Medical Systems) linear accele...

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Autores principales: Akino, Yuichi, Mizuno, Hirokazu, Isono, Masaru, Tanaka, Yoshihiro, Masai, Norihisa, Yamamoto, Toshijiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964782/
https://www.ncbi.nlm.nih.gov/pubmed/31816176
http://dx.doi.org/10.1002/acm2.12791
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author Akino, Yuichi
Mizuno, Hirokazu
Isono, Masaru
Tanaka, Yoshihiro
Masai, Norihisa
Yamamoto, Toshijiro
author_facet Akino, Yuichi
Mizuno, Hirokazu
Isono, Masaru
Tanaka, Yoshihiro
Masai, Norihisa
Yamamoto, Toshijiro
author_sort Akino, Yuichi
collection PubMed
description PURPOSE: Detector‐dependent interinstitutional variations of the beam data may lead to uncertainties of the delivered dose to patients. Here we evaluated the inter‐unit variability of the flattened and flattening filter‐free (FFF) beam data of multiple TrueBeam (Varian Medical Systems) linear accelerators focusing on the small‐field dosimetry. METHODS: The beam data of 6‐ and 10‐MV photon beams with and without flattening filter measured for modeling of an iPLAN treatment planning system (BrainLAB) were collected from 12 institutions — ten HD120 Multileaf Collimator (MLC) and two Millennium120 MLC. Percent‐depth dose (PDD), off‐center ratio (OCR), and detector output factors (OF (det)) measured with different detectors were evaluated. To investigate the detector‐associated effects, we evaluated the inter‐unit variations of the OF (det) before and after having applied the output correction factors provided by the International Atomic Energy Agency (IAEA) Technical Reports Series no. 483. RESULTS: PDD measured with a field size of 5 × 5 mm(2) showed that the data measured using an ionization chamber had variations exceeding 1% from the median values. The maximum difference from median value was 2.87% for 10 MV photon beam. The maximum variations of the penumbra width for OCR with 10 × 10 mm(2) field size were 0.97 mm. The OF (det) showed large variations exceeding 15% for a field size of 5 × 5 mm(2). When the output correction factors were applied to the OF (det), the variations were greatly reduced. The relative difference of almost all field output factors were within ± 5% from the median field output factors. CONCLUSION: In this study, the inter‐unit variability of small‐field dosimetry was evaluated for TrueBeam linear accelerators. The variations were large at a field size of 5 × 5 mm(2), and most occurred in a detector‐dependent manner.
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spelling pubmed-69647822020-01-27 Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis Akino, Yuichi Mizuno, Hirokazu Isono, Masaru Tanaka, Yoshihiro Masai, Norihisa Yamamoto, Toshijiro J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Detector‐dependent interinstitutional variations of the beam data may lead to uncertainties of the delivered dose to patients. Here we evaluated the inter‐unit variability of the flattened and flattening filter‐free (FFF) beam data of multiple TrueBeam (Varian Medical Systems) linear accelerators focusing on the small‐field dosimetry. METHODS: The beam data of 6‐ and 10‐MV photon beams with and without flattening filter measured for modeling of an iPLAN treatment planning system (BrainLAB) were collected from 12 institutions — ten HD120 Multileaf Collimator (MLC) and two Millennium120 MLC. Percent‐depth dose (PDD), off‐center ratio (OCR), and detector output factors (OF (det)) measured with different detectors were evaluated. To investigate the detector‐associated effects, we evaluated the inter‐unit variations of the OF (det) before and after having applied the output correction factors provided by the International Atomic Energy Agency (IAEA) Technical Reports Series no. 483. RESULTS: PDD measured with a field size of 5 × 5 mm(2) showed that the data measured using an ionization chamber had variations exceeding 1% from the median values. The maximum difference from median value was 2.87% for 10 MV photon beam. The maximum variations of the penumbra width for OCR with 10 × 10 mm(2) field size were 0.97 mm. The OF (det) showed large variations exceeding 15% for a field size of 5 × 5 mm(2). When the output correction factors were applied to the OF (det), the variations were greatly reduced. The relative difference of almost all field output factors were within ± 5% from the median field output factors. CONCLUSION: In this study, the inter‐unit variability of small‐field dosimetry was evaluated for TrueBeam linear accelerators. The variations were large at a field size of 5 × 5 mm(2), and most occurred in a detector‐dependent manner. John Wiley and Sons Inc. 2019-12-09 /pmc/articles/PMC6964782/ /pubmed/31816176 http://dx.doi.org/10.1002/acm2.12791 Text en © 2019 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Akino, Yuichi
Mizuno, Hirokazu
Isono, Masaru
Tanaka, Yoshihiro
Masai, Norihisa
Yamamoto, Toshijiro
Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis
title Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis
title_full Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis
title_fullStr Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis
title_full_unstemmed Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis
title_short Small‐field dosimetry of TrueBeam(TM) flattened and flattening filter‐free beams: A multi‐institutional analysis
title_sort small‐field dosimetry of truebeam(tm) flattened and flattening filter‐free beams: a multi‐institutional analysis
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964782/
https://www.ncbi.nlm.nih.gov/pubmed/31816176
http://dx.doi.org/10.1002/acm2.12791
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