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Obstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors

PURPOSE: Obstructive sleep apnea and hypopnea syndrome (OSAHS) is poorly documented in Sub-Saharan Africa, especially in the hospital setting. The aim of this study was to determine its prevalence and to investigate the associated factors in patients admitted in a tertiary referral hospital in Camer...

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Detalles Bibliográficos
Autores principales: Poka-Mayap, Virginie, Balkissou Adamou, Dodo, Massongo, Massongo, Voufouo Sonwa, Steve, Alime, Jacqueline, Moutlen, Ben Patrick Michel, Kongnyu Njamnshi, Alfred, Noseda, Andre, Pefura-Yone, Eric Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964861/
https://www.ncbi.nlm.nih.gov/pubmed/31945127
http://dx.doi.org/10.1371/journal.pone.0227778
Descripción
Sumario:PURPOSE: Obstructive sleep apnea and hypopnea syndrome (OSAHS) is poorly documented in Sub-Saharan Africa, especially in the hospital setting. The aim of this study was to determine its prevalence and to investigate the associated factors in patients admitted in a tertiary referral hospital in Cameroon. METHODS: In this cross-sectional study conducted in the Cardiology, Endocrinology and Neurology departments of the Yaounde Central Hospital; all patients aged 21 and older were included consecutively. A sample of randomly selected patients was recorded using a portable sleep monitoring device (PMD). OSAHS was defined as apnea-hypopnea index (AHI) ≥ 5/hour (with > 50% of events being obstructive) and moderate to severe OSAHS as an AHI > 15/hour. Logistic regression was used to identify factors associated to OSAHS. RESULTS: Of the 359 patients included, 202 (56.3%) patients were women. The mean age (standard deviation) was 58 (16) years. The prevalence of OSAHS assessed by PMD (95% CI) was 57.7% (48.5–66.9%), 53.8% in men and 62.7% in women (p = 0.44). The median (25(th)-75(th) percentiles) AHI, body mass index and Epworth Sleepiness Scale score of OSAHS patients were 17 (10.6–26.9)/hour, 27.4 (24.7–31.6) kg/m(2) and 7 (5–9) respectively. The only factor associated to moderate to severe OSAHS was hypertension [odds ratio (95% CI)]: 3.24 (1.08–9.72), p = 0.036. CONCLUSION: OSAHS is a common condition in patients in this health care centre of Cameroon. In the hospital setting, screening for OSAHS in patients with hypertension is recommended.