The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion

The migration of cancer cells is highly regulated by the biomechanical properties of their local microenvironment. Using 3D scaffolds of simple composition, several aspects of cancer cell mechanosensing (signal transduction, EMC remodeling, traction forces) have been separately analyzed in the conte...

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Detalles Bibliográficos
Autores principales: Anguiano, María, Morales, Xabier, Castilla, Carlos, Pena, Alejandro Rodríguez, Ederra, Cristina, Martínez, Martín, Ariz, Mikel, Esparza, Maider, Amaveda, Hippolyte, Mora, Mario, Movilla, Nieves, Aznar, José Manuel García, Cortés-Domínguez, Iván, Ortiz-de-Solorzano, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964905/
https://www.ncbi.nlm.nih.gov/pubmed/31945053
http://dx.doi.org/10.1371/journal.pone.0220019

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