Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation

Viral infections impose major stress on the host cell. In response, stress pathways can rapidly deploy defence mechanisms by shutting off the protein synthesis machinery and triggering the accumulation of mRNAs into stress granules to limit the use of energy and nutrients. Because this threatens vir...

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Detalles Bibliográficos
Autores principales: Brocard, Michèle, Iadevaia, Valentina, Klein, Philipp, Hall, Belinda, Lewis, Glenys, Lu, Jia, Burke, James, Willcocks, Margaret M., Parker, Roy, Goodfellow, Ian G., Ruggieri, Alessia, Locker, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964919/
https://www.ncbi.nlm.nih.gov/pubmed/31905230
http://dx.doi.org/10.1371/journal.ppat.1008250

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