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Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients

Ibuprofen is a commonly used medication in the United States and is used both by prescription and over the counter, while hypokalemia is a life-threatening condition caused by various etiologies, one of which is the side effect of medications. Ibuprofen is well-known for its various nephrotoxic side...

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Autores principales: Thammineni, Nikhila, Kathi, Pradeep R, Sharma, Aditi, Jawed, Areeba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964961/
https://www.ncbi.nlm.nih.gov/pubmed/31970034
http://dx.doi.org/10.7759/cureus.6404
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author Thammineni, Nikhila
Kathi, Pradeep R
Sharma, Aditi
Jawed, Areeba
author_facet Thammineni, Nikhila
Kathi, Pradeep R
Sharma, Aditi
Jawed, Areeba
author_sort Thammineni, Nikhila
collection PubMed
description Ibuprofen is a commonly used medication in the United States and is used both by prescription and over the counter, while hypokalemia is a life-threatening condition caused by various etiologies, one of which is the side effect of medications. Ibuprofen is well-known for its various nephrotoxic side effects, including hyperkalemia as a common electrolyte abnormality, however, renal tubular acidosis leading to hypokalemia with the use of ibuprofen has been reported rarely. We present here two cases of life-threatening hypokalemia due to over-the-counter use of large doses of ibuprofen and describe its management.
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spelling pubmed-69649612020-01-22 Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients Thammineni, Nikhila Kathi, Pradeep R Sharma, Aditi Jawed, Areeba Cureus Nephrology Ibuprofen is a commonly used medication in the United States and is used both by prescription and over the counter, while hypokalemia is a life-threatening condition caused by various etiologies, one of which is the side effect of medications. Ibuprofen is well-known for its various nephrotoxic side effects, including hyperkalemia as a common electrolyte abnormality, however, renal tubular acidosis leading to hypokalemia with the use of ibuprofen has been reported rarely. We present here two cases of life-threatening hypokalemia due to over-the-counter use of large doses of ibuprofen and describe its management. Cureus 2019-12-17 /pmc/articles/PMC6964961/ /pubmed/31970034 http://dx.doi.org/10.7759/cureus.6404 Text en Copyright © 2019, Thammineni et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Nephrology
Thammineni, Nikhila
Kathi, Pradeep R
Sharma, Aditi
Jawed, Areeba
Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients
title Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients
title_full Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients
title_fullStr Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients
title_full_unstemmed Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients
title_short Ibuprofen Overuse Leading to Life-threatening Hypokalemia Associated with Renal Tubular Acidosis in Two Patients
title_sort ibuprofen overuse leading to life-threatening hypokalemia associated with renal tubular acidosis in two patients
topic Nephrology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964961/
https://www.ncbi.nlm.nih.gov/pubmed/31970034
http://dx.doi.org/10.7759/cureus.6404
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