Cargando…

Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain Injury

Traumatic brain injury (TBI) is a commonly occurring injury in sports, victims of motor vehicle accidents, and falls. TBI has become a pressing public health concern with no specific therapeutic treatment. Mild TBI (mTBI), which accounts for approximately 90% of all TBI cases, may frequently lead to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bader, Miaad, Li, Yazhou, Tweedie, David, Shlobin, Nathan A., Bernstein, Adi, Rubovitch, Vardit, Tovar-y-Romo, Luis B., DiMarchi, Richard D., Hoffer, Barry J., Greig, Nigel H., Pick, Chaim G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965031/ https://www.ncbi.nlm.nih.gov/pubmed/31998717 http://dx.doi.org/10.3389/fcell.2019.00356

Ejemplares similares

Cognitive Impairments Accompanying Rodent Mild Traumatic Brain Injury Involve p53-Dependent Neuronal Cell Death and Are Ameliorated by the Tetrahydrobenzothiazole PFT-α
por: Rachmany, Lital, et al.
Publicado: (2013)

Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice
por: Baratz, Renana, et al.
Publicado: (2015)

Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration
por: Rachmany, Lital, et al.
Publicado: (2017)

GM1 ganglioside prevents axonal regeneration inhibition and cognitive deficits in a mouse model of traumatic brain injury
por: Benady, Amit, et al.
Publicado: (2018)

Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms
por: Tweedie, David, et al.
Publicado: (2016)

Restoring GM1 ganglioside expression ameliorates axonal outgrowth inhibition and cognitive impairments induced by blast traumatic brain injury
por: Rubovitch, Vardit, et al.
Publicado: (2017)

No Significant Effects of Cellphone Electromagnetic Radiation on Mice Memory or Anxiety: Some Mixed Effects on Traumatic Brain Injured Mice
por: Qubty, Doaa, et al.
Publicado: (2021)

Contextual fear response is modulated by M-type K+ channels and is associated with subtle structural changes of the axon initial segment in hippocampal GABAergic neurons
por: Ruiz, Sara Arciniegas, et al.
Publicado: (2023)

Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury
por: Tweedie, David, et al.
Publicado: (2020)

Nano-PSO Administration Attenuates Cognitive and Neuronal Deficits Resulting from Traumatic Brain Injury
por: Qubty, Doaa, et al.
Publicado: (2022)

Effect of mild blast-induced TBI on dendritic architecture of the cortex and hippocampus in the mouse
por: Ratliff, Whitney A., et al.
Publicado: (2020)

Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes
por: Capozzi, Megan E, et al.
Publicado: (2018)

Ketogenic Diet as a potential treatment for traumatic brain injury in mice
por: Har-Even, Meirav, et al.
Publicado: (2021)

Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)
por: Baratz-Goldstein, Renana, et al.
Publicado: (2016)

Cognitive and Cellular Effects of Combined Organophosphate Toxicity and Mild Traumatic Brain Injury
por: Freidin, Dor, et al.
Publicado: (2023)

The Influence of Incretin Mimetics on Cardiovascular Risk Factors in Diabetes
por: Kinalska, Ida, et al.
Publicado: (2012)

The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia
por: Glotfelty, Elliot J., et al.
Publicado: (2023)

Recent Advances in Incretin-Based Pharmacotherapies for the Treatment of Obesity and Diabetes
por: Tan, Qiming, et al.
Publicado: (2022)

Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine
por: Hoffer, Barry J., et al.
Publicado: (2017)

Metabolic Effects of the Incretin Mimetic Exenatide in the Treatment of Type 2 Diabetes
por: Schnabel, Catherine A, et al.
Publicado: (2006)

Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor
por: Eger, Michal, et al.
Publicado: (2019)

Author Correction: Bone Anabolic Response in the Calvaria Following Mild Traumatic Brain Injury is Mediated by the Cannabinoid-1 Receptor
por: Eger, Michal, et al.
Publicado: (2020)

Post-Injury Neuroprotective Effects of the Thalidomide Analog 3,6′-Dithiothalidomide on Traumatic Brain Injury
por: Batsaikhan, Buyandelger, et al.
Publicado: (2019)

Incretin Mimetics: Promising New Therapeutic Options in the Treatment of Type 2 Diabetes
por: Gleeson, Jeremy M., et al.
Publicado: (2005)

Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat
por: Wang, Jin-Ya, et al.
Publicado: (2016)

Erratum to: Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat
por: Wang, Jing-Ya, et al.
Publicado: (2016)

Anti-atherosclerotic effect of incretin mimetics: a meta-analysis of randomized controlled trials
por: Barbarawi, Mahmoud, et al.
Publicado: (2018)

Incretin mimetics: a novel therapeutic option for patients with type 2 diabetes – a review
por: Hansen, Katrine B, et al.
Publicado: (2010)

GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
por: Wright, Shane C., et al.
Publicado: (2023)

How should we think about the unprecedented weight loss efficacy of incretin-mimetic drugs?
por: Gou, Yang, et al.
Publicado: (2023)

Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation
por: Tweedie, David, et al.
Publicado: (2011)

Uncertainties around incretin-based therapies: A literature review
por: Al Tulaihi, Bader, et al.
Publicado: (2017)

Neuroprotective Activity of Sitagliptin via Reduction of Neuroinflammation beyond the Incretin Effect: Focus on Alzheimer's Disease
por: Wiciński, Michał, et al.
Publicado: (2018)

Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease
por: Lilja, Anna M., et al.
Publicado: (2013)

Incretin Concepts
por: Bloomgarden, Zachary T.
Publicado: (2010)

Inflammation and incretins
por: Hatwal, Amitabh
Publicado: (2012)

Role of Thrombin in Central Nervous System Injury and Disease
por: Shlobin, Nathan A., et al.
Publicado: (2021)

GIP: An Inconsequential Incretin or Not?
por: Pratley, Richard E.
Publicado: (2010)

Pleiotropic effects of incretins
por: Gupta, Vishal
Publicado: (2012)

Incretin-based therapies
por: Stonehouse, Anthony H, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2hgk56k72cnihh3jb0j67s1pfd