PAK Kinases Target Sortilin and Modulate Its Sorting

The multifunctional type 1 receptor sortilin is involved in endocytosis and intracellular transport of ligands. The short intracellular domain of sortilin binds several cytoplasmic adaptor proteins (e.g., the AP-1 complex and GGA1 to -3), most of which target two well-defined motifs: a C-terminal ac...

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Detalles Bibliográficos
Autores principales: Pallesen, Lone Tjener, Gustafsen, Camilla, Cramer, Jacob Flyvholm, Petersen, Steen Vang, Thirup, Søren Skou, Madsen, Peder, Petersen, Claus Munck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965034/
https://www.ncbi.nlm.nih.gov/pubmed/31767632
http://dx.doi.org/10.1128/MCB.00411-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965034/
https://www.ncbi.nlm.nih.gov/pubmed/31767632
http://dx.doi.org/10.1128/MCB.00411-19

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