Cargando…

Induction of E6AP by microRNA-302c dysregulation inhibits TGF-β-dependent fibrogenesis in hepatic stellate cells

Hepatic stellate cells (HSCs) are essential for liver fibrosis. E6 associated protein (E6AP) is one of the E3-ubiquitin-protein ligase and has been studied in proliferation and cellular stress. Currently, no information is available on the role of E6AP on transforming growth factor-β (TGF-β) signali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji Young, Kim, Kyu Min, Yang, Ji Hye, Cho, Sam Seok, Kim, Seung Jung, Park, Su Jung, Ahn, Sang‐Gun, Lee, Gum Hwa, Yang, Jin Won, Lim, Sung Chul, Kang, Keon Wook, Ki, Sung Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965100/ https://www.ncbi.nlm.nih.gov/pubmed/31949242 http://dx.doi.org/10.1038/s41598-019-57322-w

Ejemplares similares

Parkin-Mediated Mitophagy by TGF-β Is Connected with Hepatic Stellate Cell Activation
por: Lee, Ji Hyun, et al.
Publicado: (2023)

TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
por: Dewidar, Bedair, et al.
Publicado: (2019)

Role of Metabolism in Hepatic Stellate Cell Activation and Fibrogenesis
por: Hou, Wei, et al.
Publicado: (2018)

Serine Protease HtrA2/Omi Deficiency Impairs Mitochondrial Homeostasis and Promotes Hepatic Fibrogenesis via Activation of Hepatic Stellate Cells
por: Hur, Wonhee, et al.
Publicado: (2019)

Regulation of Hepatic Stellate Cells and Fibrogenesis by Fibroblast Growth Factors
por: Schumacher, Justin D., et al.
Publicado: (2016)

Expression of angiotensinogen during hepatic fibrogenesis and its effect on hepatic stellate cells
por: Lu, Ping, et al.
Publicado: (2011)

DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis
por: Pan, Xue-yin, et al.
Publicado: (2018)

Kindlin-2 regulates hepatic stellate cells activation and liver fibrogenesis
por: Yu, Jun, et al.
Publicado: (2018)

Thrombin cleavage of osteopontin controls activation of hepatic stellate cells and is essential for liver fibrogenesis
por: Cui, Guangying, et al.
Publicado: (2018)

Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction
por: Shi, Chanjuan, et al.
Publicado: (2014)

The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis
por: Bansal, Ruchi, et al.
Publicado: (2015)

Berberine Inhibition of Fibrogenesis in a Rat Model of Liver Fibrosis and in Hepatic Stellate Cells
por: Wang, Ning, et al.
Publicado: (2016)

Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis
por: Cipriani, Sabrina, et al.
Publicado: (2017)

Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis
por: Zhang, Bichen, et al.
Publicado: (2021)

Reversion of in vivo fibrogenesis by novel chromone scaffolds
por: Kim, Han-Soo, et al.
Publicado: (2019)

Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage
por: Mogler, Carolin, et al.
Publicado: (2015)

An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells
por: Qian, Hui, et al.
Publicado: (2015)

Rap1 regulates hepatic stellate cell migration through the modulation of RhoA activity in response to TGF-β1
por: Moon, Mi-Young, et al.
Publicado: (2019)

Altered AKAP12 expression in portal fibroblasts and liver sinusoids mediates transition from hepatic fibrogenesis to fibrosis resolution
por: Lee, Hye Shin, et al.
Publicado: (2018)

Proteomic landscape of TGF-β1-induced fibrogenesis in renal fibroblasts
por: Zhou, Shujun, et al.
Publicado: (2020)

The function of integrin linked-kinase (ILK) in normal and activated stellate cells–implications for fibrogenesis in wound healing
por: Shafiei, Mahnoush S., et al.
Publicado: (2011)

Blocking of SMAD4 expression by shRNA effectively inhibits fibrogenesis of human hepatic stellate cells
por: Khanizadeh, Sayyad, et al.
Publicado: (2015)

Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis
por: Bhattacharya, Dipankar, et al.
Publicado: (2021)

EPRS1 Controls the TGF-β Signaling Pathway via Interaction with TβRI in Hepatic Stellate Cell
por: Yoon, Ina, et al.
Publicado: (2023)

Fibrogenesis
por: Harington, J. S.
Publicado: (1974)

Fibrogenesis
por: Munger, John S., et al.
Publicado: (2010)

Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells
por: Chong, Lee-Won, et al.
Publicado: (2015)

Inhibition of Hepatic Stellate Cell Activation Suppresses Tumorigenicity of Hepatocellular Carcinoma in Mice
por: Kang, Min-Jung, et al.
Publicado: (2021)

Heterogeneity of Hepatic Stellate Cells in Fibrogenesis of the Liver: Insights from Single-Cell Transcriptomic Analysis in Liver Injury
por: Zhang, Wenjun, et al.
Publicado: (2021)

Somatostatin Therapy Improves Stellate Cell Activation and Early Fibrogenesis in a Preclinical Model of Extended Major Hepatectomy
por: Hessheimer, Amelia J., et al.
Publicado: (2021)

Hepatic Fibrosis Inhibitory Effect of Peptides Isolated from Navicula incerta on TGF-β1 Induced Activation of LX-2 Human Hepatic Stellate Cells
por: Kang, Kyong-Hwa, et al.
Publicado: (2013)

The Combination of piR-823 and Eukaryotic Initiation Factor 3 B (EIF3B) Activates Hepatic Stellate Cells via Upregulating TGF-β1 in Liver Fibrogenesis
por: Tang, Xuechan, et al.
Publicado: (2018)

The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis
por: Seidenberg, Jemima, et al.
Publicado: (2021)

Endothelin-converting enzyme-1 expression in acute and chronic liver injury in fibrogenesis
por: Cho, Tae-Jun, et al.
Publicado: (2019)

Chemoembolization for Single Large Hepatocellular Carcinoma with Preserved Liver Function: Analysis of Factors Predicting Clinical Outcomes in a 302 Patient Cohort
por: Kim, Gun Ha, et al.
Publicado: (2021)

EphB2 receptor tyrosine kinase promotes hepatic fibrogenesis in mice via activation of hepatic stellate cells
por: Mimche, Patrice N., et al.
Publicado: (2018)

HDAC4 stimulates MRTF-A expression and drives fibrogenesis in hepatic stellate cells by targeting miR-206
por: Han, Xinrui, et al.
Publicado: (2017)

mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance
por: Meroni, Marica, et al.
Publicado: (2019)

MiR-34c promotes hepatic stellate cell activation and Liver Fibrogenesis by suppressing ACSL1 expression
por: Li, Binbin, et al.
Publicado: (2021)

Regulatory mechanisms of TGF‐β1‐induced fibrogenesis of human alveolar epithelial cells
por: Shi, Lin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0p4786e8b713r2oa15jmhv22np