Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles

Therapy resistance and recurrence in high-grade gliomas are driven by their populations of glioma stem cells (GSCs). Thus, detailed molecular characterization of GSCs is needed to develop more effective therapies. We conducted a study to identify differences in the splicing profile and expression of...

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Detalles Bibliográficos
Autores principales: Guardia, Gabriela D. A., Correa, Bruna R., Araujo, Patricia Rosa, Qiao, Mei, Burns, Suzanne, Penalva, Luiz O. F., Galante, Pedro A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965107/
https://www.ncbi.nlm.nih.gov/pubmed/31969990
http://dx.doi.org/10.1038/s41525-019-0108-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965107/
https://www.ncbi.nlm.nih.gov/pubmed/31969990
http://dx.doi.org/10.1038/s41525-019-0108-5

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