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Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles
Therapy resistance and recurrence in high-grade gliomas are driven by their populations of glioma stem cells (GSCs). Thus, detailed molecular characterization of GSCs is needed to develop more effective therapies. We conducted a study to identify differences in the splicing profile and expression of...
Autores principales: | Guardia, Gabriela D. A., Correa, Bruna R., Araujo, Patricia Rosa, Qiao, Mei, Burns, Suzanne, Penalva, Luiz O. F., Galante, Pedro A. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965107/ https://www.ncbi.nlm.nih.gov/pubmed/31969990 http://dx.doi.org/10.1038/s41525-019-0108-5 |
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