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Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress

Overload of palmitic acids is linked to the dysregulation of ceramide metabolism in nonalcoholic steatohepatitis (NASH), and ceramides are important bioactive lipids mediating the lipotoxicity of palmitic acid in NASH. However, much remains unclear about the role of ceramidases that catalyze the hyd...

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Detalles Bibliográficos
Autores principales:	Wang, Kai, Li, Chuanjiang, Lin, Xinxin, Sun, Hang, Xu, Ruijuan, Li, Qingping, Wei, Yiran, Li, Yiyi, Qian, Jianping, Liu, Cuiting, Zhang, Qifan, Yu, Sheng, Cui, Zhonglin, Huang, Xixin, Zhu, Bili, Zhou, Jie, Mao, Cungui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965144/ https://www.ncbi.nlm.nih.gov/pubmed/31949129 http://dx.doi.org/10.1038/s41419-019-2214-9

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