Targeting Forward and Reverse EphB4/EFNB2 Signaling by a Peptide with Dual Functions

The tyrosine kinase receptor EphB4 is frequently overexpressed in ovarian and other solid tumors and is involved in interactions between tumor cells and the tumor microenvironment, contributing to metastasis. Trans-interaction between EphB4 and its membrane-bound ligand ephrin B2 (EFNB2) mediates bi...

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Detalles Bibliográficos
Autores principales: Xiong, Chiyi, Wen, Yunfei, Zhao, Jun, Yin, Dengke, Xu, Lingyun, Chelariu-Raicu, Anca, Yao, Cody, Leng, Xiaohong, Liu, Jinsong, Chaudhari, Rajan R., Zhang, Shuxing, Sood, Anil K., Li, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965176/
https://www.ncbi.nlm.nih.gov/pubmed/31949258
http://dx.doi.org/10.1038/s41598-020-57477-x

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