The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change

In pharmacogenomic studies of quantitative change, any association between genetic variants and the pretreatment (baseline) measurement can bias the estimate of effect between those variants and drug response. A putative solution is to adjust for baseline. We conducted a series of genome-wide associ...

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Detalles Bibliográficos
Autores principales: Oni-Orisan, Akinyemi, Haldar, Tanushree, Ranatunga, Dilrini K., Medina, Marisa W., Schaefer, Catherine, Krauss, Ronald M., Iribarren, Carlos, Risch, Neil, Hoffmann, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965183/
https://www.ncbi.nlm.nih.gov/pubmed/31969989
http://dx.doi.org/10.1038/s41525-019-0109-4

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