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Compound 15c, a Novel Dual Inhibitor of EGFR(L858R/T790M) and FGFR1, Efficiently Overcomes Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance of Non-Small-Cell Lung Cancers
In the past decades, epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) had been proved as an effective treatment strategy for the patients with EGFR-mutated non-small-cell lung cancer (NSCLC). However, the tolerance for the EGFR-TKI always occurred after continuous administrati...
Autores principales: | Chen, Gaozhi, Bao, Yuyan, Weng, Qiaoyou, Zhao, Yingxin, Lu, Xiaoyao, Fu, Lili, Chen, Lingfeng, Liu, Zhiguo, Zhang, Xiaomin, Liang, Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965315/ https://www.ncbi.nlm.nih.gov/pubmed/31998131 http://dx.doi.org/10.3389/fphar.2019.01533 |
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