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Personalized Treatment of H3K27M-Mutant Pediatric Diffuse Gliomas Provides Improved Therapeutic Opportunities

Diffuse gliomas with K27M histone mutations (H3K27M glioma) are generally characterized by a fatal prognosis, particularly affecting the pediatric population. Based on the molecular heterogeneity observed in this tumor type, personalized treatment is considered to substantially improve therapeutic o...

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Detalles Bibliográficos
Autores principales:	Gojo, Johannes, Pavelka, Zdenek, Zapletalova, Danica, Schmook, Maria T., Mayr, Lisa, Madlener, Sibylle, Kyr, Michal, Vejmelkova, Klara, Smrcka, Martin, Czech, Thomas, Dorfer, Christian, Skotakova, Jarmila, Azizi, Amedeo A., Chocholous, Monika, Reisinger, Dominik, Lastovicka, David, Valik, Dalibor, Haberler, Christine, Peyrl, Andreas, Noskova, Hana, Pál, Karol, Jezova, Marta, Veselska, Renata, Kozakova, Sarka, Slaby, Ondrej, Slavc, Irene, Sterba, Jaroslav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965319/ https://www.ncbi.nlm.nih.gov/pubmed/31998633 http://dx.doi.org/10.3389/fonc.2019.01436

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