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High Frequency Production of T Cell-Derived iPSC Clones Capable of Generating Potent Cytotoxic T Cells

Current adoptive T cell therapies conducted in an autologous setting are costly, time-consuming, and depend on the quality of the patient’s T cells, and thus it would be highly beneficial to develop an allogeneic strategy. To this aim, we have developed a method by which cytotoxic T lymphocytes (CTL...

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Detalles Bibliográficos
Autores principales: Nagano, Seiji, Maeda, Takuya, Ichise, Hiroshi, Kashima, Soki, Ohtaka, Manami, Nakanishi, Mahito, Kitawaki, Toshio, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi, Masuda, Kyoko, Kawamoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965501/
https://www.ncbi.nlm.nih.gov/pubmed/31970197
http://dx.doi.org/10.1016/j.omtm.2019.12.006