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Ginkgolic Acid, a SUMO-1 Inhibitor, Inhibits the Progression of Oral Squamous Cell Carcinoma by Alleviating SUMOylation of SMAD4

Small ubiquitin-related modifiers (SUMO) represent a class of ubiquitin-like proteins that are conjugated, like ubiquitin, by a set of enzymes to form cellular regulatory proteins, and play key roles in the control of cell proliferation, differentiation, and apoptosis. We found that ginkgolic acid (...

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Detalles Bibliográficos
Autores principales: Liu, Ke, Wang, Xinhuan, Li, Duo, Xu, Dongyang, Li, Dezhi, Lv, Zhiyong, Zhao, Dan, Chu, Wen-Feng, Wang, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965518/
https://www.ncbi.nlm.nih.gov/pubmed/31970286
http://dx.doi.org/10.1016/j.omto.2019.12.005