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Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency
Type 1 diabetes affects 20 million patients worldwide. Insulin is the primary and commonly the sole therapy for type 1 diabetes. However, only a minority of patients attain the targeted glucose control and reduced adverse events. We tested urocortin 2 gene transfer as single-agent therapy for insuli...
Autores principales: | Gao, Mei Hua, Giamouridis, Dimosthenis, Lai, N. Chin, Guo, Tracy, Xia, Bing, Kim, Young Chul, Huu, Viet Anh Nguyen, Skowronska-Krawczyk, Dorota, Lantier, Louise, Bhargava, Raag, Hammond, H. Kirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965520/ https://www.ncbi.nlm.nih.gov/pubmed/31970200 http://dx.doi.org/10.1016/j.omtm.2019.12.002 |
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