Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate

Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of con...

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Autores principales: Kochan, Travis J., Ozer, Egon A., Pincus, Nathan B., Fitzpatrick, Margaret A., Hauser, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965585/
https://www.ncbi.nlm.nih.gov/pubmed/31948967
http://dx.doi.org/10.1128/MRA.01408-19
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author Kochan, Travis J.
Ozer, Egon A.
Pincus, Nathan B.
Fitzpatrick, Margaret A.
Hauser, Alan R.
author_facet Kochan, Travis J.
Ozer, Egon A.
Pincus, Nathan B.
Fitzpatrick, Margaret A.
Hauser, Alan R.
author_sort Kochan, Travis J.
collection PubMed
description Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.
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spelling pubmed-69655852020-02-03 Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate Kochan, Travis J. Ozer, Egon A. Pincus, Nathan B. Fitzpatrick, Margaret A. Hauser, Alan R. Microbiol Resour Announc Genome Sequences Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains. American Society for Microbiology 2020-01-16 /pmc/articles/PMC6965585/ /pubmed/31948967 http://dx.doi.org/10.1128/MRA.01408-19 Text en Copyright © 2020 Kochan et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Kochan, Travis J.
Ozer, Egon A.
Pincus, Nathan B.
Fitzpatrick, Margaret A.
Hauser, Alan R.
Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
title Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
title_full Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
title_fullStr Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
title_full_unstemmed Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
title_short Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate
title_sort complete genome sequence of klebsiella pneumoniae strain tk421, a conjugative hypervirulent isolate
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965585/
https://www.ncbi.nlm.nih.gov/pubmed/31948967
http://dx.doi.org/10.1128/MRA.01408-19
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