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Metabolomics Reveals that Cysteine Metabolism Plays a Role in Celastrol-Induced Mitochondrial Apoptosis in HL-60 and NB-4 Cells

Recently, celastrol has shown great potential for inducing apoptosis in acute myeloid leukemia cells, especially acute promyelocytic leukaemia cells. However, the mechanism is poorly understood. Metabolomics provides an overall understanding of metabolic mechanisms to illustrate celastrol's mec...

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Detalles Bibliográficos
Autores principales:	Chen, Minjian, Yang, Jing, Li, Lei, Hu, Yanhui, Lu, Xiaomei, Sun, Rongli, Wang, Yubang, Wang, Xinru, Zhang, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965619/ https://www.ncbi.nlm.nih.gov/pubmed/31949255 http://dx.doi.org/10.1038/s41598-019-57312-y

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