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Increased frequency of PD-1(hi)CXCR5(-) T cells and B cells in patients with newly diagnosed IgA nephropathy
Recent research has identified a population of PD-1(hi)CXCR5(−) ‘peripheral helper’ T (Tph) cells that simulate plasma cell differentiation by interactions between IL-21 and SLAMF5. However, the alteration of circulating Tph and CD138(+) B in IgA nephropathy (IgAN) remains poorly understood. Flow cy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965632/ https://www.ncbi.nlm.nih.gov/pubmed/31949193 http://dx.doi.org/10.1038/s41598-019-57324-8 |