ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD

Hydrogen sulfide (H(2)S) is now widely considered the third endogenous gasotransmitter and plays critical roles in cancer biological processes. In this study, we demonstrate that 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT-OH), the most widely used moiety for synthesising slow-releasing H(2)S...

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Detalles Bibliográficos
Autores principales: Cai, Fangfang, Xu, Huangru, Cao, Nini, Zhang, Xiangyu, Liu, Jia, Lu, Yanyan, Chen, Jia, Yang, Yunwen, Cheng, Jian, Hua, Zi-Chun, Zhuang, Hongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965651/
https://www.ncbi.nlm.nih.gov/pubmed/31949127
http://dx.doi.org/10.1038/s41419-020-2222-9

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