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Cancer Is Associated with Alterations in the Three-Dimensional Organization of the Genome
The human genome is organized into topologically associating domains (TADs), which represent contiguous regions with a higher frequency of intra-interactions as opposed to inter-interactions. TADs contribute to gene expression regulation by restricting the interactions between their regulatory eleme...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966451/ https://www.ncbi.nlm.nih.gov/pubmed/31783642 http://dx.doi.org/10.3390/cancers11121886 |