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Temozolomide in Glioblastoma Therapy: Role of Apoptosis, Senescence and Autophagy. Comment on Strobel et al., Temozolomide and Other Alkylating Agents in Glioblastoma Therapy. Biomedicines 2019, 7, 69
Temozolomide, a DNA methylating drug, is currently being used first-line in glioblastoma therapy. Although the mode of action of this so-called S(N)1 alkylating agent is well described, including the types of induced DNA damage triggering the DNA damage response and survival and death pathways, some...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966492/ https://www.ncbi.nlm.nih.gov/pubmed/31717973 http://dx.doi.org/10.3390/biomedicines7040090 |